San Clemente, CA, Nov. 17, 2020 (GLOBE NEWSWIRE) — via NewMediaWire — The coronavirus disease 2019 (COVID-19) pandemic has placed the world in a tailspin, which the healthcare industry has responded to in kind with the development and rapid deployment of tests designed to detect infection. Many of these tests help clinicians and researchers accurately identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for COVID-19.
And while these tests have been crucial in identifying and tracking cases of infection and disease-related morbidity and mortality, they aren’t without their potential drawbacks.
Types of COVID-19 Tests
Several new methods have been developed to diagnose COVID-19, many of which have their own alternative methods of administration and unique benefits:
Antigen Rapid, point-of-care diagnostic tests: These tests, which can be classified as antigen or, rely on a mucus sample obtained from the throat or nose and is analyzed is used in a rapid device similar to a Flu test, at a clinic or physician’s office. Results from these tests can often be available within minutes.
Antibody Rapid, point-of-care diagnostic tests: These tests, which can be classified as serological, rely on fingertip blood obtained from the patient with results in minutes.
Molecular: These tests, which are classified as molecular rely of nasal or throat swab samples with results as soon as 90 minutes.
Diagnostic Tests: Molecular vs Antigen Tests
There are two main types of COVID-19 tests which identify the virus, either the Partial Genetic Marker of the Virus in the Molecular Test or Specific Protein found on the Virus in the Rapid Antigen IgA Test.
Getting a test for COVID-19 can be challenging for some people, especially considering the rapid evolution on testing guidance on testing options. While each test features its own limitations, molecular tests are perhaps the most effective strategies available, but take the longest amount of time and must be done in a lab, or hospital in most cases.
Below is an overview of these different tests, including what they can do to identify the disease and their limitations.
RT-PCR
The RT-PCR is the most common test that is frequently used to detect the virus’s Partial Genetic Marker of the Virus in the body. Using this test, patients can know whether or not they have an active COVID-19 infection and can adjust their lifestyle accordingly (i.e., quarantine or not).
Pros
Minimally invasive – performed using nasal swabs and throat swabs.
Allows for social distancing – while some molecular tests, including RT-PCR, are sometimes conducted at a hospital or clinic, swabs can also be taken from the patient’s car or at home and evaluated at a urgent care, clinic, doctor’s office or hospital.
Fewer false negatives in some instances – deep nasal swabs will have fewer false negatives compared with other tests, such as throat swabs or saliva tests
Cons
Long turnaround times – in some instances, RT-PCR tests can yield results in the same day or within one to two days, but test results taking up to one to two weeks have been reported during the pandemic
False negatives – molecular tests have been shown to produce results that say the patient doesn’t have the virus when they actually do; the rates of false-positives have ranged from 2% to 37%. If too many cycles are run, there is a high false positive rate as well.
Uncomfortable for some people – deep nasal swabs can be uncomfortable for some people, especially small children
Antigen Tests
Antigen tests, which are performed using a nasal or throat swab, help detect specific protein fragments residing on the surface of the virus.
Pros
Rapid results: The test uses technology similar to that used in an Influenza test and yields results within minutes. Tests are point of care and can be performed at urgent cares.
“This test could be used at point-of-care settings, like a doctor’s office, emergency room, or some schools. This test has been authorized for use in patients suspected of COVID-19 by their healthcare provider within seven days of symptom onset. Given the simple nature of this test, it is likely that these tests could be made broadly available. Global can increase production to 120,000 tests per day, once approved.”
https://www.fda.gov/news-events/press-announcements/covid-19-update-fda-authorizes-first-diagnostic-test-where-results-can-be-read-directly-testing-card
Cons
High false-negative rate: Antigen tests produce higher false-negative rates than molecular RT-PCR tests, with some evidence suggesting rates as high as 50%.
Antibody Tests
Antibody tests look for specific antibodies generated by the immune system in response to a virus, including SARS-CoV-2. Antibodies are proteins that the body produces to combat active invading viruses and active infections. This test is also known as a serological test, blood test and serology test and involves taking a sample with a fingertip blood.
Pros
The Antibody test detects if a person has or has had the Corona Virus. The point-of-care (POC) antibody test uses fingertip blood and can give the results with 5 to 10 minutes.
“Binding antibodies can be detected with blood tests starting about one week after the initial infection. If antibodies are found, it’s extremely likely that the person has been infected with the COVID-19 coronavirus.” www.health.harvard.edu
Cons
It can take several days or weeks to develop antibodies after viral exposure, depending on the individual.
Global WholeHealth Partners Corp offers all the formats for testing CoViD 19 SARS 2. Global has the Antibody IgG/IgM Rapid antibody, including the POC (Point of Care), the rtPCR CoViD 19 SARS test, which works on any machine, all these tests are FDA EUA AUTHORIZED.
Global also offers for international sales the Antigen Rapid IgA test, which is not FDA EUA Authorized.
Call 1-877-568-GWHP (4947) to become a distributor or buy FDA EUA Authorized SARS-COV-2 IgG/IgM Antibody Whole Blood, Serum and Plasma Rapid Test kits, or the Point of Care IgG/IgM fingertip blood format or the rtPCR test.
About Global WholeHealth Partners Corp.:
Global WholeHealth Partners Corp. provides cutting edge technology using In-vitro Diagnostic (IVD) Real-Time PCR Machines that detects in about 60 minutes and Rapid Diagnostic Testing (RDT) Serum Plasma, Whole Blood and Fingertip blood that detect between 10-15 minutes, which predict diseases ahead of its industry competitors.
For international testing, which is not sold in the USA, but has a Certificate of Exportability by the FDA Certificate No. 2260-11-2019, are tests like Rapid Ebola, Rapid Dengue Fever Antibody and Antigen, Rapid Tuberculosis (TB), Rapid Malaria, and many other rapid tests.
The rapid antibody test allows results to be available in 15 minutes or less. By so doing, GWHP has led the fight against vector-borne terminal diseases such as Ebola, ZIKA, Dengue, Malaria, Influenza and Tuberculosis, Corona Viruses, and among other vector-borne diseases. Our vision is to lead the industry in infectious disease diagnostics and provide molecular solutions that lessen the time to diagnose medical results and empower healthcare professionals.
For more details: https://gwhpcorp.com
Media Contact:
Name: Charles Strongo,
CEO, Global WholeHealth Partners Corp.
Email: [email protected]
Forward-Looking Statements
This press release contains “forward-looking statements.” Such statements may be preceded by the words “intends,” “may,” “will,” “plans,” “expects,” “anticipates,” “projects,” “predicts,” “estimates,” “aims,” “believes,” “hopes,” “potential” or similar words. Forward-looking statements are not guarantees of future performance, are based on certain assumptions and are subject to various known and unknown risks and uncertainties, many of which are beyond the Company’s control, and cannot be predicted or quantified and consequently, actual results may differ materially from those expressed or implied by such forward-looking statements. Such risks and uncertainties include, without limitation, risks and uncertainties associated with (i) market acceptance of our existing and new products, (ii) negative clinical trial results or lengthy product delays in key markets, (iii) an inability to secure regulatory approvals for the sale of our products, (iv) intense competition in the medical device industry from much larger, multinational companies, (v) product liability claims, (vi) product malfunctions, (vii) our limited manufacturing capabilities and reliance on subcontractors for assistance, (viii) insufficient or inadequate reimbursement by governmental and other third party payers for our products, (ix) our efforts to successfully obtain and maintain intellectual property protection covering our products, which may not be successful, (x) legislative or regulatory reform of the healthcare system in both the U.S. and foreign jurisdictions, (xi) our reliance on single suppliers for certain product components, (xii) the fact that we will need to raise additional capital to meet our business requirements in the future and that such capital raising may be costly, dilutive or difficult to obtain and (xiii) the fact that we conduct business in multiple foreign jurisdictions, exposing us to foreign currency exchange rate fluctuations, logistical and communications challenges, burdens and costs of compliance with foreign laws and political and economic instability in each jurisdiction. More detailed information about the Company and the risk factors that may affect the realization of forward-looking statements is set forth in the Company’s filings with the Securities and Exchange Commission (SEC), including the Company’s Annual Report on Form 10-K and its Quarterly Reports on Form 10-Q. Investors and security holders are urged to read these documents free of charge on the SEC’s web site at http://www.sec.gov. The Company assumes no obligation to publicly update or revise its forward-looking statements as a result of new information, future events or otherwise.
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